Periprosthetic Infections following total joint arthroplasty are among the most serious complications and constitute a major challenge with respect to correct diagnosis and treatment. The treatment options depend on patient characteristics, infecting germs and the onset of the infection. The training course Revision in Arthroplasty (septic) for orthopaedic surgeons gives an overview of the current status of the causes, available diagnostic tools and treatment options of an infected joint replacement.